DJ010 | CAS#unknown | CD4 & sortilin inhibitor

MedKoo Cat#: 465425 | Name: DJ010

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DJ010 is a CD4 and sortilin inhibitor. It displayed activity for sortilin down-modulation and reduction of progranulin-induced breast cancer stem cell propagation.

Chemical Structure

DJ010

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465425

Name: DJ010

CAS#: unknown

Chemical Formula: C32H47N3O6S2

Exact Mass: 633.2906

Molecular Weight: 633.86

Elemental Analysis: C, 60.64; H, 7.47; N, 6.63; O, 15.14; S, 10.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

DJ010; DJ 010; DJ-010;

IUPAC/Chemical Name

2-(4-((9-(cyclohexylmethyl)-3-methylene-5-tosyl-1,5,9-triazacyclododecan-1-yl)sulfonyl)phenoxy)ethan-1-ol

InChi Key

PRSSFRICNRPSSN-UHFFFAOYSA-N

InChi Code

InChI=1S/C32H47N3O6S2/c1-27-10-14-31(15-11-27)42(37,38)34-20-6-18-33(26-29-8-4-3-5-9-29)19-7-21-35(25-28(2)24-34)43(39,40)32-16-12-30(13-17-32)41-23-22-36/h10-17,29,36H,2-9,18-26H2,1H3

SMILES Code

C=C1CN(S(=O)(C2=CC=C(C)C=C2)=O)CCCN(CCCN(S(=O)(C3=CC=C(OCCO)C=C3)=O)C1)CC4CCCCC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 633.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Berger K, Pauwels E, Parkinson G, Landberg G, Le T, Demillo VG, Lumangtad LA, Jones DE, Islam MA, Olsen R, Kapri T, Intasiri A, Vermeire K, Rhost S, Bell TW. Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds. J Med Chem. 2021 Aug 24. doi: 10.1021/acs.jmedchem.1c00943. Epub ahead of print. PMID: 34428050.