MedKoo Cat#: 414804 | Name: PD 118576

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PD 118576 is a new cytotoxic antibiotic obtained from the culture broth of a Streptomyces sp.

Chemical Structure

PD 118576
PD 118576
CAS#100632-37-9

Theoretical Analysis

MedKoo Cat#: 414804

Name: PD 118576

CAS#: 100632-37-9

Chemical Formula: C33H52O8

Exact Mass: 576.3662

Molecular Weight: 576.77

Elemental Analysis: C, 68.72; H, 9.09; O, 22.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
PD 118576; PD118576; PD-118576; PD118,576; PD 118,576; PD-118,576
IUPAC/Chemical Name
(3E,5Z,11E,13Z)-16-((E)-3,9-dihydroxy-4,8-dimethyl-5-oxodec-6-en-2-yl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one
InChi Key
LZUOOFGZMKQIEU-MZNNIAHHSA-N
InChi Code
InChI=1S/C33H52O8/c1-19-12-11-13-28(39-9)32(25(7)31(37)24(6)27(35)15-14-21(3)26(8)34)41-33(38)29(40-10)18-20(2)17-23(5)30(36)22(4)16-19/h11-15,17-18,21-26,28,30-32,34,36-37H,16H2,1-10H3/b13-11-,15-14+,19-12+,20-17-,29-18+
SMILES Code
COC1/C=C\C=C(CC(C(C(/C=C(\C=C(C(OC1C(C(C(C(/C=C/C(C(O)C)C)=O)C)O)C)=O)\OC)C)C)O)C)/C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 576.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wilton JH, Hokanson GC, French JC. PD 118,576: a new antitumor macrolide antibiotic. J Antibiot (Tokyo). 1985 Nov;38(11):1449-52. doi: 10.7164/antibiotics.38.1449. PMID: 3841121.