PD-0299685 | CAS# 313651-33-1 | vasomotor symptoms

MedKoo Cat#: 414802 | Name: PD-0299685

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PD-0299685 was undergoing a phase II trial (NCT00314964) for the treatment of vasomotor symptoms, such as hot flushes, associated with menopause.

Chemical Structure

PD-0299685

CAS#313651-33-1

Theoretical Analysis

MedKoo Cat#: 414802

Name: PD-0299685

CAS#: 313651-33-1

Chemical Formula: C10H21NO2

Exact Mass: 187.1572

Molecular Weight: 187.28

Elemental Analysis: C, 64.13; H, 11.30; N, 7.48; O, 17.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PD-0299685; PD0299685; PD 0299685

IUPAC/Chemical Name

(3S,5R)-3-(aminomethyl)-5-methyloctanoic acid

InChi Key

KKXFMWXZXDUYBF-BDAKNGLRSA-N

InChi Code

InChI=1S/C10H21NO2/c1-3-4-8(2)5-9(7-11)6-10(12)13/h8-9H,3-7,11H2,1-2H3,(H,12,13)/t8-,9+/m1/s1

SMILES Code

CCC[C@H](C[C@@H](CC(O)=O)CN)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 187.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nickel JC, Crossland A, Davis E, Haab F, Mills IW, Rovner E, Scholfield D, Crook T. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188(3):817-23. doi: 10.1016/j.juro.2012.05.010. Epub 2012 Jul 19. PMID: 22818144. 2: Chuang YC, Chermansky C, Kashyap M, Tyagi P. Investigational drugs for bladder pain syndrome (BPS) / interstitial cystitis (IC). Expert Opin Investig Drugs. 2016;25(5):521-9. doi: 10.1517/13543784.2016.1162290. Epub 2016 Mar 22. PMID: 26940379.