UZH2 is a Potent and Selective METTL3 Inhibitor. UZH2 shows target engagement in cells and is able to reduce the m6A/A level of polyadenylated RNA in MOLM-13 (acute myeloid leukemia) and PC-3 (prostate cancer) cell lines.
MedKoo Cat#: 465418
Name: UZH2
CAS#: 2756566-45-5
Chemical Formula: C27H37F2N7O
Exact Mass: 513.3028
Molecular Weight: 513.64
Elemental Analysis: C, 63.14; H, 7.26; F, 7.40; N, 19.09; O, 3.11
The following data is based on the product molecular weight 513.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
