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MedKoo Cat#: 414753 | Name: Panuramine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Panuramine is an antidepressant which was synthesized in 1981 by Wyeth. It acts as a potent and selective serotonin reuptake inhibitor (SSRI).

Chemical Structure

Panuramine
Panuramine
CAS#80349-58-2

Theoretical Analysis

MedKoo Cat#: 414753

Name: Panuramine

CAS#: 80349-58-2

Chemical Formula: C24H25N3O2

Exact Mass: 387.1947

Molecular Weight: 387.48

Elemental Analysis: C, 74.39; H, 6.50; N, 10.84; O, 8.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Panuramine; Panuramina; Panuraminum
IUPAC/Chemical Name
1-Benzoyl-3-(1-(2-naphthylmethyl)-4-piperidyl)urea
InChi Key
AQFFJGJVFJCQQL-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25N3O2/c28-23(20-7-2-1-3-8-20)26-24(29)25-22-12-14-27(15-13-22)17-18-10-11-19-6-4-5-9-21(19)16-18/h1-11,16,22H,12-15,17H2,(H2,25,26,28,29)
SMILES Code
O=C(NC1CCN(CC2=CC=C3C=CC=CC3=C2)CC1)NC(C4=CC=CC=C4)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 387.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Blurton PA, Broadhurst AM, Cross JA, Ennis C, Wood MD, Wyllie MG. Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine in the brain of the rat. Neuropharmacology. 1984 Sep;23(9):1049-52. doi: 10.1016/0028-3908(84)90127-8. PMID: 6514142. 2: Wood MD, Broadhurst AM, Wyllie MG. Examination of the relationship between the uptake system for 5-hydroxytryptamine and the high-affinity [3H]imipramine binding site--I. Inhibition by drugs. Neuropharmacology. 1986 May;25(5):519-25. doi: 10.1016/0028-3908(86)90178-4. PMID: 3016589. 3: Wood MD. Examination of the relationship between the uptake site for 5-hydroxytryptamine and the high affinity binding site for [3H]imipramine. II. The role of sodium ions. Neuropharmacology. 1987 Aug;26(8):1081-5. doi: 10.1016/0028-3908(87)90251-6. PMID: 2958719.