MedKoo Cat#: 577222 | Name: Metazide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Metazide, a isonicotinic acid hydrazide derivative, is a tuberculostatic agent. Metazid causes damage to the membrane of Mycobacterium tuberculosis, inhibits metabolic and oxidative processes, inhibits the synthesis of nucleic acids, inhibiting the proliferation of bacteria inside and outside the cell.

Chemical Structure

Metazide
CAS#1707-15-9

Theoretical Analysis

MedKoo Cat#: 577222

Name: Metazide

CAS#: 1707-15-9

Chemical Formula: C13H14N6O2

Exact Mass: 286.1178

Molecular Weight: 286.29

Elemental Analysis: C, 54.54; H, 4.93; N, 29.36; O, 11.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Metazide; Ro2-4969; Ro-2-4969; Ro 2-4969
IUPAC/Chemical Name
N',N'''-methylenedi(isonicotinohydrazide)
InChi Key
WWCIFIOLOMCRET-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H14N6O2/c20-12(10-1-5-14-6-2-10)18-16-9-17-19-13(21)11-3-7-15-8-4-11/h1-8,16-17H,9H2,(H,18,20)(H,19,21)
SMILES Code
O=C(NNCNNC(=O)c1ccncc1)c2ccncc2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 286.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shapiro AA, Meksin VA, Abilev SK, Akin'shina LP, Fonshteĭn LM. Izuchenie mutagennoĭ aktivnosti protivotuberkuleznykh preparatov: gidrazida izonikotinovoĭ kisloty i ego proizvodnykh [Mutagenic activity of antitubercular preparations: isonicotinic acid hydrazide and its derivatives]. Tsitol Genet. 1978 Jul- Aug;12(4):343-8. Russian. PMID: 360538.