MedKoo Cat#: 465286 | Name: 93-O17S
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

93-O17S is a chalcogen-containing cationic lipidoid. It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and stimulation of interferon genes (STING) activation in a B16/F10 murine melanoma model.

Chemical Structure

93-O17S
93-O17S
CAS#2227008-67-3

Theoretical Analysis

MedKoo Cat#: 465286

Name: 93-O17S

CAS#: 2227008-67-3

Chemical Formula: C44H83N3O4S2

Exact Mass: 781.5825

Molecular Weight: 782.29

Elemental Analysis: C, 67.56; H, 10.69; N, 5.37; O, 8.18; S, 8.20

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
93-O17S; 93O17S; 93 O17S;
IUPAC/Chemical Name
bis(2-(tetradecylthio)ethyl) 3,3'-((3-(1H-imidazol-1-yl)propyl)azanediyl)dipropionate
InChi Key
OLOIOPYNTGMAAP-UHFFFAOYSA-N
InChi Code
InChI=1S/C44H83N3O4S2/c1-3-5-7-9-11-13-15-17-19-21-23-25-38-52-40-36-50-43(48)28-33-46(31-27-32-47-35-30-45-42-47)34-29-44(49)51-37-41-53-39-26-24-22-20-18-16-14-12-10-8-6-4-2/h30,35,42H,3-29,31-34,36-41H2,1-2H3
SMILES Code
O=C(CCN(CCC(OCCSCCCCCCCCCCCCCC)=O)CCCN1C=NC=C1)OCCSCCCCCCCCCCCCCC
Appearance
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Chloroform 100.0 127.83
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 782.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen J, Qiu M, Ye Z, Nyalile T, Li Y, Glass Z, Zhao X, Yang L, Chen J, Xu Q. In situ cancer vaccination using lipidoid nanoparticles. Sci Adv. 2021 May 5;7(19):eabf1244. doi: 10.1126/sciadv.abf1244. PMID: 33952519; PMCID: PMC8099179.