Org 9616 | CAS# 119302-18-0 | steroidal neuromuscular blocking drug

MedKoo Cat#: 414622 | Name: Org 9616

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Org 9616 is a steroidal neuromuscular blocking drug.

Chemical Structure

Org 9616

CAS#119302-18-0

Theoretical Analysis

MedKoo Cat#: 414622

Name: Org 9616

CAS#: 119302-18-0

Chemical Formula: C36H61BrN2O4

Exact Mass: 664.3815

Molecular Weight: 665.79

Elemental Analysis: C, 64.94; H, 9.24; Br, 12.00; N, 4.21; O, 9.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Org 9616; Org9616; Org-9616

IUPAC/Chemical Name

Piperidinium, 1-((2beta,3alpha,5alpha,16beta,17alpha)-3-(acetyloxy)-17-(1-oxobutoxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-, bromide

InChi Key

ZFJFKPJKLLLVSR-HELRLQSOSA-M

InChi Code

InChI=1S/C36H61N2O4.BrH/c1-6-13-33(40)42-34-31(38(5)20-11-8-12-21-38)23-29-27-15-14-26-22-32(41-25(2)39)30(37-18-9-7-10-19-37)24-36(26,4)28(27)16-17-35(29,34)3;/h26-32,34H,6-24H2,1-5H3;1H/q+1;/p-1/t26-,27+,28-,29-,30-,31-,32-,34+,35-,36-;/m0./s1

SMILES Code

C[N+]1([C@H]2C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@H]2OC(CCC)=O)CCCCC1.[Br-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 665.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Khuenl-Brady K, Castagnoli KP, Canfell PC, Caldwell JE, Agoston S, Miller RD. The neuromuscular blocking effects and pharmacokinetics of ORG 9426 and ORG 9616 in the cat. Anesthesiology. 1990 Apr;72(4):669-74. doi: 10.1097/00000542-199004000-00016. PMID: 1969717. 2: Cason B, Baker DG, Hickey RF, Miller RD, Agoston S. Cardiovascular and neuromuscular effects of three steroidal neuromuscular blocking drugs in dogs (ORG 9616, ORG 9426, ORG 9991). Anesth Analg. 1990 Apr;70(4):382-8. doi: 10.1213/00000539-199004000-00007. PMID: 1969251. 3: Muir AW, Houston J, Marshall RJ, Bowman WC, Marshall IG. A comparison of the neuromuscular blocking and autonomic effects of two new short-acting muscle relaxants with those of succinylcholine in the anesthetized cat and pig. Anesthesiology. 1989 Mar;70(3):533-40. doi: 10.1097/00000542-198903000-00026. PMID: 2564263. 4: Boumén U, Marshall I. Farmakologiia nekotorykh aminosteroidnykh miorelaksantov [Pharmacology of various aminosteroidal muscle relaxants]. Farmakol Toksikol. 1989 May-Jun;52(3):29-33. Russian. PMID: 2571518.