MLRI | CAS#unknown | Cationic lipid

MedKoo Cat#: 465236 | Name: MLRI

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MLRI is a cationic lipid for RNA and vaccine delivery

Chemical Structure

MLRI

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465236

Name: MLRI

CAS#: unknown

Chemical Formula: C33H66INO5

Exact Mass: 683.3986

Molecular Weight: 683.80

Elemental Analysis: C, 57.96; H, 9.73; I, 18.56; N, 2.05; O, 11.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MLRI;

IUPAC/Chemical Name

2-(dodecanoyloxy)-N-(2-hydroxyethyl)-N,N-dimethyl-3-(tetradecanoyloxy)propan-1-aminium iodide

InChi Key

ATZSPYLAVQRGFK-UHFFFAOYSA-M

InChi Code

InChI=1S/C33H66NO5.HI/c1-5-7-9-11-13-15-16-18-19-21-23-25-32(36)38-30-31(29-34(3,4)27-28-35)39-33(37)26-24-22-20-17-14-12-10-8-6-2;/h31,35H,5-30H2,1-4H3;1H/q+1;/p-1

SMILES Code

C[N+](C)(CC(COC(CCCCCCCCCCCCC)=O)OC(CCCCCCCCCCC)=O)CCO.[I-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 683.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kalil J, Wollman EE. Role of class I and class II antigens in the allogenic stimulation: class I and class II recognition in allogenic stimulation; blocking of MLR by monoclonal antibodies and F(ab')2 fragments. Cell Immunol. 1983 Jul 15;79(2):367-73. doi: 10.1016/0008-8749(83)90078-3. PMID: 6223710. 2: Hecker JG, Hall LL, Irion VR. Nonviral gene delivery to the lateral ventricles in rat brain: initial evidence for widespread distribution and expression in the central nervous system. Mol Ther. 2001 Mar;3(3):375-84. doi: 10.1006/mthe.2001.0272. PMID: 11273780. 3: Hauck ES, Zou S, Scarfo K, Nantz MH, Hecker JG. Whole animal in vivo imaging after transient, nonviral gene delivery to the rat central nervous system. Mol Ther. 2008 Nov;16(11):1857-64. doi: 10.1038/mt.2008.183. Epub 2008 Aug 26. PMID: 18728638; PMCID: PMC2575133.