LC-001 | CAS#unknown | WIN site inhibitor probe

MedKoo Cat#: 465213 | Name: LC-001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LC-001 is a Probe of WIN site inhibitor and PROTAC of WDR5.

Chemical Structure

LC-001

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465213

Name: LC-001

CAS#: unknown

Chemical Formula: C41H52ClFN8O4S

Exact Mass: 806.3505

Molecular Weight: 807.43

Elemental Analysis: C, 60.99; H, 6.49; Cl, 4.39; F, 2.35; N, 13.88; O, 7.93; S, 3.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LC-001; LC001; LC 001;

IUPAC/Chemical Name

5-amino-2-chloro-4-fluoro-3-methyl-N-(4-(4-methylpiperazin-1-yl)-4'-(6-(5-((3aS,4R,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)-[1,1'-biphenyl]-3-yl)benzamide

InChi Key

VPTAKNRDGAVVAF-DECSONGXSA-N

InChi Code

InChI=1S/C41H52ClFN8O4S/c1-25-37(42)29(23-30(44)38(25)43)40(54)47-31-22-27(13-16-33(31)51-20-18-50(2)19-21-51)26-11-14-28(15-12-26)46-36(53)10-4-3-7-17-45-35(52)9-6-5-8-34-39-32(24-56-34)48-41(55)49-39/h11-16,22-23,32,34,39H,3-10,17-21,24,44H2,1-2H3,(H,45,52)(H,46,53)(H,47,54)(H2,48,49,55)/t32-,34+,39-/m0/s1

SMILES Code

CN1CCN(C2=CC=C(C3=CC=C(NC(CCCCCNC(CCCC[C@H]4SC[C@@](N5)([H])[C@]4([H])NC5=O)=O)=O)C=C3)C=C2NC(C6=CC(N)=C(F)C(C)=C6Cl)=O)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 807.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chen ZF, Qin QP, Qin JL, Zhou J, Li YL, Li N, Liu YC, Liang H. Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis. J Med Chem. 2015 Jun 11;58(11):4771-89. doi: 10.1021/acs.jmedchem.5b00444. Epub 2015 Jun 2. PMID: 25988535.