MEN-10710 | CAS# 159269-60-0 | Biochemical

MedKoo Cat#: 577117 | Name: MEN-10710

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MEN-10710 is a biochemical with antitumor activity.

Chemical Structure

MEN-10710

CAS#159269-60-0

Theoretical Analysis

MedKoo Cat#: 577117

Name: MEN-10710

CAS#: 159269-60-0

Chemical Formula: C41H51Cl3N12O5

Exact Mass: 896.3171

Molecular Weight: 898.29

Elemental Analysis: C, 54.82; H, 5.72; Cl, 11.84; N, 18.71; O, 8.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MEN10710; MEN 10710; MEN-10710

IUPAC/Chemical Name

1H-Pyrrole-2-carboxamide, N-(5-(((5-(((5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-4-((4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutyl)amino)-1-methyl-, monohydrochloride

InChi Key

HFZXPAXHZFTMIR-UHFFFAOYSA-N

InChi Code

InChI=1S/C41H50Cl2N12O5.ClH/c1-51-23-28(19-32(51)38(57)46-15-12-36(44)45)48-40(59)34-21-30(25-53(34)3)50-41(60)35-20-29(24-54(35)4)49-39(58)33-18-27(22-52(33)2)47-37(56)7-5-6-26-8-10-31(11-9-26)55(16-13-42)17-14-43;/h8-11,18-25H,5-7,12-17H2,1-4H3,(H3,44,45)(H,46,57)(H,47,56)(H,48,59)(H,49,58)(H,50,60);1H

SMILES Code

Cl.Cn1cc(NC(=O)c2cc(NC(=O)c3cc(NC(=O)c4cc(NC(=O)CCCc5ccc(cc5)N(CCCl)CCCl)cn4C)cn3C)cn2C)cc1C(=O)NCCC(=N)N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 898.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Bigioni M, Salvatore C, Palma C, Manzini S, Animati F, Lombardi P, Pratesi G, Supino R, Zunino F. Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin. Anticancer Drugs. 1997 Oct;8(9):845-52. doi: 10.1097/00001813-199710000-00005. PMID: 9402311. 2. Ciucci A, Manzini S, Lombardi P, Arcamone F. Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues. Nucleic Acids Res. 1996 Jan 15;24(2):311-5. doi: 10.1093/nar/24.2.311. PMID: 8628655; PMCID: PMC145640. 3. Ciucci A, Manzini S, Lombardi P, Arcamone F. Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues. Nucleic Acids Res. 1996 Jan 15;24(2):311-5. doi: 10.1093/nar/24.2.311. PMID: 8628655; PMCID: PMC145640.