Related CAS #
86767-75-1 (saccharin); 71251-02-0 (free base); 70775-75-6 (2HCl)
Synonym
Octenidine Free Base; Octenidinum; Octenidina
IUPAC/Chemical Name
1-Octanamine, N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-
InChi Key
ZVXNYZWXUADSRV-UHFFFAOYSA-N
InChi Code
InChI=1S/C36H62N4/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2/h23-26,31-34H,3-22,27-30H2,1-2H3
SMILES Code
CCCCCCCC/N=C1C=CN(CCCCCCCCCCN(C=C/2)C=CC2=N/CCCCCCCC)C=C/1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
550.92
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Shepherd MJ, Moore G, Wand ME, Sutton JM, Bock LJ. Pseudomonas aeruginosa adapts to octenidine in the laboratory and a simulated clinical setting, leading to increased tolerance to chlorhexidine and other biocides. J Hosp Infect. 2018 Nov;100(3):e23-e29. doi: 10.1016/j.jhin.2018.03.037. Epub 2018 Mar 31. PMID: 29614247.
7: Szostak K, Czogalla A, Przybyło M, Langner M. New lipid formulation of octenidine dihydrochloride. J Liposome Res. 2018 Jun;28(2):106-111. doi: 10.1080/08982104.2016.1275678. Epub 2017 Jan 18. PMID: 28006995.
8: Melhorn S, Staubach P. Octenidindihydrochlorid : Das Antiseptikum, das nicht jede Grundlage mag [Octenidine dihydrochloride : The antiseptic that does not like every base formulation]. Hautarzt. 2018 May;69(5):427-429. German. doi: 10.1007/s00105-018-4139-0. PMID: 29532135.
9: Htun HL, Hon PY, Holden MTG, Ang B, Chow A. Chlorhexidine and octenidine use, carriage of qac genes, and reduced antiseptic susceptibility in methicillin- resistant Staphylococcus aureus isolates from a healthcare network. Clin Microbiol Infect. 2019 Sep;25(9):1154.e1-1154.e7. doi: 10.1016/j.cmi.2018.12.036. Epub 2019 Jan 6. PMID: 30625411.
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