Related CAS #
82-88-2 (free base); 569-59-5 (tartrate); 5503-08-2 (HCl)
Synonym
Phenindamine; NU1504; NU-1504; NU 1504
IUPAC/Chemical Name
1H-Indeno(2,1-c)pyridine, 2,3,4,9-tetrahydro-2-methyl-9-phenyl-
InChi Key
ISFHAYSTHMVOJR-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H19N/c1-20-12-11-16-15-9-5-6-10-17(15)19(18(16)13-20)14-7-3-2-4-8-14/h2-10,19H,11-13H2,1H3
SMILES Code
CN1CCC2=C(C(C3=CC=CC=C3)C4=C2C=CC=C4)C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
261.37
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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7: DAILEY RE, WAY EL, PARIKH JR, SUNG C, HOWIE DL. Absorption, distribution and excretion of phenindamine (thephorin). Proc Soc Exp Biol Med. 1950 Jun;74(2):394-8. doi: 10.3181/00379727-74-17919. PMID: 15440834.
8: Martínez-Gómez MA, Carril-Avilés MM, Sagrado S, Villanueva-Camañas RM, Medina-Hernández MJ. Characterization of antihistamine-human serum protein interactions by capillary electrophoresis. J Chromatogr A. 2007 Apr 20;1147(2):261-9. doi: 10.1016/j.chroma.2007.02.054. Epub 2007 Feb 22. PMID: 17339039.
9: Abdallah A, White HD. Comparative study of the anorectic activity of phenindamine d-amphetamine and fenfluramine in different species. Arch Int Pharmacodyn Ther. 1970 Dec;188(2):271-83. PMID: 5523473.
10: SCHLOSS EM. Thephorin (phenindamine) in the treatment of gastrointestinal allergy. Gastroenterology. 1949 Oct;13(4):311-8. PMID: 15392896.
