d2T | CAS#3416-05-5 | Antiviral nucleoside analog

MedKoo Cat#: 464988 | Name: d2T

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

d2T is a nucleoside analog of thymidine that has antiviral activity. It inhibits HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC50 = 0.17 µM).2 3′-deoxy Thymidine (1, 3, 10, or 30 µM) reduces viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).

Chemical Structure

d2T

CAS#3416-05-5

Theoretical Analysis

MedKoo Cat#: 464988

Name: d2T

CAS#: 3416-05-5

Chemical Formula: C10H14N2O4

Exact Mass: 226.0954

Molecular Weight: 226.23

Elemental Analysis: C, 53.09; H, 6.24; N, 12.38; O, 28.29

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 450.00	2 Weeks
250mg	USD 850.00	2 Weeks

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Related CAS #

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Synonym

d2T; ddThd; 3′-deoxy Thymidine; 3′ deoxy Thymidine; 2',3'-Dideoxythymidine; DDT; Thymidine, 3'-deoxy-; Dideoxythymidine; Dideoxythymidin

IUPAC/Chemical Name

1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

InChi Key

XKKCQTLDIPIRQD-JGVFFNPUSA-N

InChi Code

InChI=1S/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h4,7-8,13H,2-3,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1

SMILES Code

[H][C@]1(O[C@@H](CC1)CO)N2C(NC(C(C)=C2)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMF	25.0	110.51
	DMF:PBS (pH 7.2) (1:5)	0.2	0.71
	DMSO	20.0	88.40

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 226.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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