MedKoo Cat#: 577073 | Name: Medorinone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Medorinone is a cardiotonic agent that has been shown to inhibit platelet aggregation.

Chemical Structure

Medorinone
Medorinone
CAS#88296-61-1

Theoretical Analysis

MedKoo Cat#: 577073

Name: Medorinone

CAS#: 88296-61-1

Chemical Formula: C9H8N2O

Exact Mass: 160.0637

Molecular Weight: 160.18

Elemental Analysis: C, 67.49; H, 5.03; N, 17.49; O, 9.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Medorinone; Win 49,016; Win49,016; Win-49,016
IUPAC/Chemical Name
1,6-Naphthyridin-2(1H)-one, 5-methyl-
InChi Key
OCCZJXAHSUCJSA-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H8N2O/c1-6-7-2-3-9(12)11-8(7)4-5-10-6/h2-5H,1H3,(H,11,12)
SMILES Code
Cc1nccc2NC(=O)C=Cc12
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 160.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Pattison A, Astley N, Eason CT, Bonner FW. A comparison of the effects of three positive inotropic agents (amrinone, milrinone and medorinone) on platelet aggregation in human whole blood. Thromb Res. 1990 Mar 15;57(6):909-18. doi: 10.1016/0049-3848(90)90157-8. PMID: 2116683. 2. Singh B, Lesher GY, Pluncket KC, Pagani ED, Bode DC, Bentley RG, Connell MJ, Hamel LT, Silver PJ. Novel cAMP PDE III inhibitors: 1,6-naphthyridin-2(1H)-ones. J Med Chem. 1992 Dec 25;35(26):4858-65. doi: 10.1021/jm00104a012. PMID: 1336055.