Synonym
Sodium aurotiosulfate; Auricidine; Auropex; Novacrysin; Solfocrisol
IUPAC/Chemical Name
sodium bis(sulfonatothio)aurate(I)
InChi Key
FJCMCHNDCIYVST-UHFFFAOYSA-J
InChi Code
InChI=1S/Au.3Na.2H2O3S2/c;;;;2*1-5(2,3)4/h;;;;2*(H2,1,2,3,4)/q4*+1;;/p-4
SMILES Code
[O-]S(=O)(S[Au-]SS(=O)([O-])=O)=O.[Na+].[Na+].[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
490.17
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Seethapathy H, Noureddine L. Calciphylaxis: Approach to Diagnosis and Management. Adv Chronic Kidney Dis. 2019 Nov;26(6):484-490. doi: 10.1053/j.ackd.2019.09.005. PMID: 31831126.
2: Shpadaruk V, Maidment G, Burova E. Pseudolymphoma Due to Gold Sodium Thiosulfate. Dermatitis. 2020 Jan/Feb;31(1):e1-e2. doi: 10.1097/DER.0000000000000507. PMID: 31905183.
3: Hamann D, Hamann C, Fowler JF Jr, Andersen KE, Bruze M. Response to: Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study. Contact Dermatitis. 2019 Aug;81(2):156. doi: 10.1111/cod.13272. Epub 2019 Apr 10. PMID: 30903666.
4: García-Arpa M, Gómez-Torrijos E, Relea-Calatayud F, Santiago-Sánchez Mateos JL, Galindo-Bonilla PA, Carmona-Rodríguez M. Cutaneous pseudolymphoma after patch test to gold sodium thiosulfate in two patients. Contact Dermatitis. 2020 May;82(5):322-324. doi: 10.1111/cod.13470. Epub 2020 Jan 27. PMID: 31925792.
5: Iwahashi Y, Takei H, Kasa Y, Uno H, Ohtoshi S, Nakada T. Histological and immunohistological study of late-onset reactions to gold sodium thiosulfate. Contact Dermatitis. 2020 Aug;83(2):163-165. doi: 10.1111/cod.13592. Epub 2020 Jun 15. PMID: 32383172.
6: Suzuki K, Yagami A, Ito A, Kanto H, Matsunaga K. Response to Hamann et al. Contact Dermatitis. 2019 Aug;81(2):157. doi: 10.1111/cod.13291. Epub 2019 May 15. PMID: 31090077.
7: Suzuki K, Yagami A, Ito A, Kato A, Miyazawa H, Kanto H, Matsunaga K. Positive reactions to gold sodium thiosulfate in patch test panels (TRUE Test) in Japan: A multicentre study. Contact Dermatitis. 2019 Feb;80(2):114-117. doi: 10.1111/cod.13105. Epub 2018 Sep 10. PMID: 30198192; PMCID: PMC6585663.
8: Gottlieb NL. Chrysotherapy. Bull Rheum Dis. 1976-1977;27(7):912-7. PMID: 829567.
9: Hamann D, Hamann CR, Hamann C, Bruze M, Fowler JF Jr. Response to: Can patch test sensitization with gold sodium thiosulfate be ruled out?-A case report. Contact Dermatitis. 2018 Jul;79(1):56-57. doi: 10.1111/cod.13006. Epub 2018 May 2. PMID: 29717789.
10: Bruze M, Björkner B, Möller H. Skin testing with gold sodium thiomalate and gold sodium thiosulfate. Contact Dermatitis. 1995 Jan;32(1):5-8. doi: 10.1111/j.1600-0536.1995.tb00831.x. PMID: 7720377.
