MedKoo Cat#: 414457 | Name: Pipamazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pipamazine is a drug of the phenothiazine class formerly used as an antiemetic. It is chemically related to chlorpromazine, but has negligible antipsychotic activity and produces few extrapyramidal side effects.

Chemical Structure

Pipamazine
Pipamazine
CAS#84-04-8

Theoretical Analysis

MedKoo Cat#: 414457

Name: Pipamazine

CAS#: 84-04-8

Chemical Formula: C21H24ClN3OS

Exact Mass: 401.1329

Molecular Weight: 401.95

Elemental Analysis: C, 62.75; H, 6.02; Cl, 8.82; N, 10.45; O, 3.98; S, 7.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Pipamazine; SC8016; SC-8016; SC 8016; SC9387; SC-9387; SC 9387
IUPAC/Chemical Name
10-(3-(4-Carbamoylpiperidino)propyl)-2-chlorophenothiazine
InChi Key
OSJJYEUEJRVVOD-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H24ClN3OS/c22-16-6-7-20-18(14-16)25(17-4-1-2-5-19(17)27-20)11-3-10-24-12-8-15(9-13-24)21(23)26/h1-2,4-7,14-15H,3,8-13H2,(H2,23,26)
SMILES Code
ClC(C=C1N2CCCN3CCC(C(N)=O)CC3)=CC=C1SC4=C2C=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: TINA LU. Pipamazine, a new antiemetic. Clin Proc Child Hosp Dist Columbia. 1960 Sep;16:257-64. PMID: 13838459. 2: DOBKIN AB. Potentiation of thiopentone anaesthesia. Comparison of promethazine, chlorpromazine, perphenazine, fluphenazine, thiopropazate, pipamazine and triflupromazine. Br J Anaesth. 1960 Sep;32:424-6. doi: 10.1093/bja/32.9.424. PMID: 13723253. 3: CANN HM, VERHULST HL. Accidental ingestion of pipamazine in young children. AMA J Dis Child. 1960 Apr;99:534-5. doi: 10.1001/archpedi.1960.02070030536017. PMID: 13807442. 4: DOBKIN AB, PURKIN N. The antisialogogue effect of phenothiazine derivatives: comparison of pecazine, perphenazine, fluphenazine, thiopropazate, pipamazine and triflupromazine. Br J Anaesth. 1960 Feb;32:57-9. doi: 10.1093/bja/32.2.57. PMID: 13817061.