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MedKoo Cat#: 577032 | Name: Zifrosilone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zifrosilone is an acetylcholinesterase inhibitor.

Chemical Structure

Zifrosilone
Zifrosilone
CAS#132236-18-1

Theoretical Analysis

MedKoo Cat#: 577032

Name: Zifrosilone

CAS#: 132236-18-1

Chemical Formula: C11H13F3OSi

Exact Mass: 246.0688

Molecular Weight: 246.30

Elemental Analysis: C, 53.64; H, 5.32; F, 23.14; O, 6.50; Si, 11.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MDL 73745; MDL-73745; MDL73745; Zifrosilone
IUPAC/Chemical Name
Ethanone, 2,2,2-trifluoro-1-(3-(trimethylsilyl)phenyl)-
InChi Key
GAPOASFZXBWUGS-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H13F3OSi/c1-16(2,3)9-6-4-5-8(7-9)10(15)11(12,13)14/h4-7H,1-3H3
SMILES Code
C[Si](C)(C)c1cccc(c1)C(=O)C(F)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 246.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cutler NR, Seifert RD, Schleman MM, Sramek JJ, Szylleyko OJ, Howard DR, Barchowsky A, Wardle TS, Brass EP. Acetylcholinesterase inhibition by zifrosilone: pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther. 1995 Jul;58(1):54-61. doi: 10.1016/0009-9236(95)90072-1. PMID: 7628183.