A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+ channel (TASK)-1 (100 µM, 53.4% ± 13, 5%, n = 5).
MedKoo Cat#: 556009
Name: A2793
CAS#: 88349-90-0
Chemical Formula: C13H12ClNO3
Exact Mass: 265.0506
Molecular Weight: 265.69
Elemental Analysis: C, 58.77; H, 4.55; Cl, 13.34; N, 5.27; O, 18.06
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 76.5 | 287.93 | |
| Ethanol | 25.0 | 94.09 |
The following data is based on the product molecular weight 265.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
