MedKoo Cat#: 414412 | Name: Nitramisole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nitramisole, an imidazothiazole derivative, is an anthelmintic. Nitramisole was effective against migrating Strongylus vulgaris larvae in ponies. Treatment of infected ponies with Nitramisole resulted both a clinical and radical cure.

Chemical Structure

Nitramisole
CAS#6363-02-6 (free base)

Theoretical Analysis

MedKoo Cat#: 414412

Name: Nitramisole

CAS#: 6363-02-6 (free base)

Chemical Formula: C11H11N3O2S

Exact Mass: 249.0572

Molecular Weight: 249.29

Elemental Analysis: C, 53.00; H, 4.45; N, 16.86; O, 12.84; S, 12.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
56689-44-2 (HCl); 6363-02-6 (free base); 6646-49-7 (free base alternate)
Synonym
Nitramisole; Nitramisol; Nitramisolum
IUPAC/Chemical Name
Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-(3-nitrophenyl)-, (+-)-
InChi Key
RFAYUIIWPKWNKY-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H11N3O2S/c15-14(16)9-3-1-2-8(6-9)10-7-13-4-5-17-11(13)12-10/h1-3,6,10H,4-5,7H2
SMILES Code
O=[N+](C1=CC(C2N=C3SCCN3C2)=CC=C1)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 249.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Slocombe JO, McCraw BM. Evaluation of pyrantel pamoate, nitramisole and avermectin B1a against migrating Strongylus vulgaris larvae. Can J Comp Med. 1980 Jan;44(1):93-100. PMID: 7397601; PMCID: PMC1320039. 2: Tian YS, Chen L, Ren ZW, Wang XY, Liang TY, Wang LS. [Observation on therapeutic effect of medicinal moxa stick moxibustion for treatment of tinea pedis]. Zhongguo Zhen Jiu. 2009 Jul;29(7):537-40. Chinese. PMID: 19835120. 3: Adaikan PG, Zaman V. In vitro activity of anthelmintic drugs and biologically active substances on Breinlia booliati. Southeast Asian J Trop Med Public Health. 1982 Jun;13(2):257-61. PMID: 7147006.