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MedKoo Cat#: 414407 | Name: Nisamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nisamycin is a manumycin group antibiotic from Streptomyces sp. K106.

Chemical Structure

Nisamycin
Nisamycin
CAS#150829-93-9

Theoretical Analysis

MedKoo Cat#: 414407

Name: Nisamycin

CAS#: 150829-93-9

Chemical Formula: C24H27NO6

Exact Mass: 425.1838

Molecular Weight: 425.48

Elemental Analysis: C, 67.75; H, 6.40; N, 3.29; O, 22.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Nisamycin
IUPAC/Chemical Name
(2E,4E,6E)-7-((1S,2R,6R)-4-((2E,4E)-5-cyclohexylpenta-2,4-dienamido)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl)hepta-2,4,6-trienoic acid
InChi Key
BUSGWUFLNHIBPT-XYBORKQMSA-N
InChi Code
InChI=1S/C24H27NO6/c26-19(13-8-7-12-17-10-4-3-5-11-17)25-18-16-24(30,23-22(31-23)21(18)29)15-9-2-1-6-14-20(27)28/h1-2,6-9,12-17,22-23,30H,3-5,10-11H2,(H,25,26)(H,27,28)/b2-1+,12-7+,13-8+,14-6+,15-9+/t22-,23-,24+/m0/s1
SMILES Code
OC(/C=C/C=C/C=C/[C@]1(C=C(C([C@@H]2O[C@H]12)=O)NC(/C=C/C=C/C3CCCCC3)=O)O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 425.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. II. Structure determination and structure-activity relationships. Hayashi K, Nakagawa M, Fujita T, Tanimori S, Nakayama M. J Antibiot (Tokyo). 1994 Oct;47(10):1110-5. doi: 10.7164/antibiotics.47.1110. PMID: 7961160 2.Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. Hayashi K, Nakagawa M, Fujita T, Tanimori S, Nakayama M. J Antibiot (Tokyo). 1993 Dec;46(12):1904-7. doi: 10.7164/antibiotics.46.1904. PMID: 8294252 No abstract available. 3.Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties. Hayashi K, Nakagawa M, Nakayama M. J Antibiot (Tokyo). 1994 Oct;47(10):1104-9. doi: 10.7164/antibiotics.47.1104. PMID: 7961159