MedKoo Cat#: 414378 | Name: Nifurmazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nifurmazole is a Chemotherapeutic

Chemical Structure

Nifurmazole
CAS#18857-59-5

Theoretical Analysis

MedKoo Cat#: 414378

Name: Nifurmazole

CAS#: 18857-59-5

Chemical Formula: C11H10N4O6

Exact Mass: 294.0600

Molecular Weight: 294.22

Elemental Analysis: C, 44.91; H, 3.43; N, 19.04; O, 32.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Nifurmazole; BRN0848847; BRN-0848847; BRN 0848847; CB10615; CB-10615; CB 10615
IUPAC/Chemical Name
3-(Hydroxymethyl)-1-((3-(5-nitro-2-furyl)allylidene)amino)hydantoin
InChi Key
IKQHXERIXMQWQK-LYTCUFGASA-N
InChi Code
InChI=1S/C11H10N4O6/c16-7-13-9(17)6-14(11(13)18)12-5-1-2-8-3-4-10(21-8)15(19)20/h1-5,16H,6-7H2/b2-1+,12-5+
SMILES Code
O=C(N1CO)N(/N=C/C=C/C2=CC=C([N+]([O-])=O)O2)CC1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Vindel J, Catalan F, Navarro J, Siou G. Activité sur Trypanosoma equiperdum, Schizotrypanum cruzi et Trypanosoma gambiense du Nifurmazole (10.615 CB) [Activity of Nifurmazole (CB 10,615) on Trypanosoma equiperdum, Schizotrypanum cruzi and Trypanosoma gambiense]. C R Acad Hebd Seances Acad Sci D. 1970 May 20;270(20):2512-5. French. PMID: 4987585. 2: Ballal S, Spry LA, Zenser TV, Davis BB. Renal handling of 5-nitrofuran nephrotoxins in the rat. Drug Metab Dispos. 1988 Nov-Dec;16(6):829-33. PMID: 2907461. 3: Zenser TV, Balasubramanian TM, Mattammal MB, Davis BB. Transport of the renal carcinogen 3-hydroxymethyl-1-([3-(5-nitro-2-furyl)allydidene]amino) hydantoin by renal cortex and cooxidative metabolism by prostaglandin endoperoxide synthetase. Cancer Res. 1981 Jun;41(6):2032-7. PMID: 6786731.