Benastatin A is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 5 µM for the rat liver enzyme). Benastatin A is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml). It induces apoptosis and cell cycle arrest at the G1/G0 phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 µM, respectively.
MedKoo Cat#: 464790
Name: Benastatin A
CAS#: 138968-85-1
Chemical Formula: C30H28O7
Exact Mass: 500.1835
Molecular Weight: 500.55
Elemental Analysis: C, 71.99; H, 5.64; O, 22.37
The following data is based on the product molecular weight 500.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
