Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC50 = 24 µg/ml for the rat liver enzyme). Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50 = 10 µg/ml). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.
MedKoo Cat#: 464789
Name: Benastatin C
CAS#: 150151-88-5
Chemical Formula: C29H28O5
Exact Mass: 456.1937
Molecular Weight: 456.54
Elemental Analysis: C, 76.30; H, 6.18; O, 17.52
The following data is based on the product molecular weight 456.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
