Democonazole is an imidazole-class antifungal agent that functions by inhibiting lanosterol 14α-demethylase (CYP51), a key enzyme in the ergosterol biosynthesis pathway in fungi. This disruption leads to defective cell membrane formation and ultimately fungal cell death. Democonazole is primarily used in agricultural settings as a fungicide to protect crops from fungal infections.
MedKoo Cat#: 576915
Name: Democonazole
CAS#: 70161-09-0
Chemical Formula: C19H15Cl3N2O2
Exact Mass: 408.0199
Molecular Weight: 409.69
Elemental Analysis: C, 55.70; H, 3.69; Cl, 25.96; N, 6.84; O, 7.81
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 0.0 | 0.00 |
The following data is based on the product molecular weight 409.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
