GS-0573 | CAS#113852-41-8 | Antiviral compound

MedKoo Cat#: 464748 | Name: GS-0573

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GS 0573 is an antiviral compound that has been studied for potential treatment of Feline herpesvirus 1 (FHV-1).

Chemical Structure

GS-0573

CAS#113852-41-8

Theoretical Analysis

MedKoo Cat#: 464748

Name: GS-0573

CAS#: 113852-41-8

Chemical Formula: C8H13N6O4P

Exact Mass: 288.0736

Molecular Weight: 288.20

Elemental Analysis: C, 33.34; H, 4.55; N, 29.16; O, 22.21; P, 10.75

Price and Availability

Size	Price	Availability
1mg	USD 90.00	Ready to ship
5mg	USD 150.00	Ready to ship
10mg	USD 250.00	Ready to ship
25mg	USD 550.00	Ready to ship
50mg	USD 950.00	Ready to ship
100mg	USD 1,650.00	Ready to ship

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Related CAS #

No Data

Synonym

GS 0573; GS0573; GS-0573;

IUPAC/Chemical Name

((2-(2,6-diamino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid

InChi Key

XHXFQGAZAVKMFF-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H13N6O4P/c9-6-5-7(13-8(10)12-6)14(3-11-5)1-2-18-4-19(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H4,9,10,12,13)

SMILES Code

O=P(O)(O)COCCN1C2=NC(N)=NC(N)=C2N=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Certificate of Analysis

View CoA: current batch, Lot# S21S12C09

QC Data

View QC data: current batch, Lot# S21S12C09

Safety Data Sheet (SDS)

View Safety Data Sheet (SDS)

Instruction

View handling instruction

Biological target:

GS 0573 is an antiviral compound that has the potential for treatment of Feline herpesvirus 1 (FHV-1).

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMSO	0.0	0.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 288.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Garré B, van der Meulen K, Nugent J, Neyts J, Croubels S, De Backer P, Nauwynck H. In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet. Vet Microbiol. 2007 May 16;122(1-2):43-51. doi: 10.1016/j.vetmic.2007.01.004. Epub 2007 Jan 14. PMID: 17276631. 2: van der Meulen K, Garré B, Croubels S, Nauwynck H. In vitro comparison of antiviral drugs against feline herpesvirus 1. BMC Vet Res. 2006 Apr 26;2:13. doi: 10.1186/1746-6148-2-13. PMID: 16640781; PMCID: PMC1475582.