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MedKoo Cat#: 576889 | Name: Martinostat

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Martinostat is a histone deacetylase imaging agent.

Chemical Structure

Martinostat
Martinostat
CAS#1629052-58-9

Theoretical Analysis

MedKoo Cat#: 576889

Name: Martinostat

CAS#: 1629052-58-9

Chemical Formula: C22H30N2O2

Exact Mass: 354.2307

Molecular Weight: 354.49

Elemental Analysis: C, 74.54; H, 8.53; N, 7.90; O, 9.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Martinostat
IUPAC/Chemical Name
2-Propenamide, N-hydroxy-3-(4-((methyl(tricycle(3.3.1.1(sup 3,7))dec-1-ylmethyl)amino)methyl)phenyl)-, (2E)-
InChi Key
WNIDBXBLQFPAJA-VOTSOKGWSA-N
InChi Code
InChI=1S/C22H30N2O2/c1-24(14-17-4-2-16(3-5-17)6-7-21(25)23-26)15-22-11-18-8-19(12-22)10-20(9-18)13-22/h2-7,18-20,26H,8-15H2,1H3,(H,23,25)/b7-6+
SMILES Code
CN(Cc1ccc(\C=C\C(=O)NO)cc1)CC23CC4CC(CC(C4)C2)C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 354.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Donovan LL, Magnussen JH, Dyssegaard A, Lehel S, Hooker JM, Knudsen GM, Hansen HD. Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain. Mol Imaging Biol. 2020 Jun;22(3):569-577. doi: 10.1007/s11307-019-01403-9. PMID: 31290052. 2. Wey HY, Wang C, Schroeder FA, Logan J, Price JC, Hooker JM. Kinetic Analysis and Quantification of [¹¹C]Martinostat for in Vivo HDAC Imaging of the Brain. ACS Chem Neurosci. 2015 May 20;6(5):708-15. doi: 10.1021/acschemneuro.5b00066. Epub 2015 Mar 25. PMID: 25768025; PMCID: PMC4439341.