Elapegademase | CAS# 1709806-75-6 | Adenosine Deaminase Inhibitor

MedKoo Cat#: 414187 | Name: Elapegademase

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Elapegademase is an Adenosine Deaminase Inhibitor

Chemical Structure

Elapegademase

CAS# 1709806-75-6

Theoretical Analysis

MedKoo Cat#: 414187

Name: Elapegademase

CAS#: 1709806-75-6

Chemical Formula: C10H20N2O5

Exact Mass: 248.1372

Molecular Weight: 248.28

Elemental Analysis: C, 48.38; H, 8.12; N, 11.28; O, 32.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Elapegademase; EZN2279; EZN 2279; EZN-2279

IUPAC/Chemical Name

N6-((2-methoxyethoxy)carbonyl)-L-lysine

InChi Key

XNGDIOBPVDBNQH-QMMMGPOBSA-N

InChi Code

InChI=1S/C10H20N2O5/c1-16-6-7-17-10(15)12-5-3-2-4-8(11)9(13)14/h8H,2-7,11H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1

SMILES Code

COCCOC(NCCCC[C@@H](C(O)=O)N)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 248.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006–. Elapegademase. 2020 Jul 20. PMID: 32697455. 2: Murguia-Favela L, Min W, Loves R, Leon-Ponte M, Grunebaum E. Comparison of elapegademase and pegademase in ADA-deficient patients and mice. Clin Exp Immunol. 2020 May;200(2):176-184. doi: 10.1111/cei.13420. Epub 2020 Feb 9. PMID: 31989577; PMCID: PMC7160653. 3: Kim DH, Lee HS, Kwon TW, Han YM, Kang NW, Lee MY, Kim DD, Kim MG, Lee JY. Single enzyme nanoparticle, an effective tool for enzyme replacement therapy. Arch Pharm Res. 2020 Jan;43(1):1-21. doi: 10.1007/s12272-020-01216-3. Epub 2020 Jan 27. PMID: 31989476.