Exp3880 | CAS# 138330-11-7 | Antagonizes angiotensin receptor AII-1 site

MedKoo Cat#: 414182 | Name: Exp3880

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Exp3880 antagonizes angiotensin receptor AII-1 site.

Chemical Structure

Exp3880

CAS# 138330-11-7

Theoretical Analysis

MedKoo Cat#: 414182

Name: Exp3880

CAS#: 138330-11-7

Chemical Formula: C21H19F3N6O

Exact Mass: 428.1572

Molecular Weight: 428.42

Elemental Analysis: C, 58.87; H, 4.47; F, 13.30; N, 19.62; O, 3.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Exp3880; EXP3880; EXP-3880

IUPAC/Chemical Name

1H-Imidazol-5-ol, 2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-4-(trifluoromethyl)-

InChi Key

ZWDWNNVKBCXTAX-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H19F3N6O/c1-2-5-17-25-18(21(22,23)24)20(31)30(17)12-13-8-10-14(11-9-13)15-6-3-4-7-16(15)19-26-28-29-27-19/h3-4,6-11,31H,2,5,12H2,1H3,(H,26,27,28,29)

SMILES Code

OC1=C(C(F)(F)F)N=C(CCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 428.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: DeNoble VJ, DeNoble KF, Spencer KR, Chiu AT, Wong PC, Timmermans PB. Non- peptide angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor: effect on a renin-induced deficit of a passive avoidance response in rats. Brain Res. 1991 Oct 11;561(2):230-5. doi: 10.1016/0006-8993(91)91599-v. PMID: 1802340. 2: Lokuta AJ, Cooper C, Gaa ST, Wang HE, Rogers TB. Angiotensin II stimulates the release of phospholipid-derived second messengers through multiple receptor subtypes in heart cells. J Biol Chem. 1994 Feb 18;269(7):4832-8. PMID: 8106454.