MedKoo Cat#: 414176 | Name: Midaflur

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Midaflur is an extremely stable 3-imidazoline derivative with central skeletal muscle relaxant and sedative properties in humans and other species of mammals, exhibiting consistently high oral bioavailability and a long duration of action.

Chemical Structure

Midaflur
Midaflur
CAS#23757-42-8

Theoretical Analysis

MedKoo Cat#: 414176

Name: Midaflur

CAS#: 23757-42-8

Chemical Formula: C7H3F12N3

Exact Mass: 357.0135

Molecular Weight: 357.10

Elemental Analysis: C, 23.54; H, 0.85; F, 63.84; N, 11.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Midaflur; EXP338; EXP-338; EXP 338
IUPAC/Chemical Name
1H-Imidazol-4-amine, 2,5-dihydro-2,2,5,5-tetrakis(trifluoromethyl)-
InChi Key
KYWMWUUMCDZISK-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H3F12N3/c8-4(9,10)2(5(11,12)13)1(20)21-3(22-2,6(14,15)16)7(17,18)19/h22H,(H2,20,21)
SMILES Code
NC1=NC(C(F)(F)F)(C(F)(F)F)NC1(C(F)(F)F)C(F)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 357.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Clark R, Lynes TE, Price WA, Smith DH, Woodward JK, Marvel JP, Vernier VG. The pharmacology and toxicology of midaflur. Toxicol Appl Pharmacol. 1971 Apr;18(4):917-43. doi: 10.1016/0041-008x(71)90239-0. PMID: 5570243. 2: Jaramillo J. Quantitative electroencephalographic and metabolic studies of midaflur, a new anesthetic agent. Am J Vet Res. 1979 Aug;40(8):1062-5. PMID: 525909. 3: Mei ZT, Zhu TC. [Central sites for the muscle relaxation activity of midaflur (author's transl)]. Zhongguo Yao Li Xue Bao. 1980 Dec;1(2):88-92. Chinese. PMID: 6461190.