A‑1293102 is a Potent and Selective BCL‑XL Inhibitor. A-1293102 exhibited picomolar binding affinity to BCL-XL and both efficiently and selectively killed BCL-XL-dependent tumor cells. A-1293102 represents one of the few distinct structural series of selective BCL-XL inhibitors, and thus serves as a useful tool for biological studies as well as a lead compound for further optimization.
MedKoo Cat#: 464720
Name: A‑1293102
CAS#: unknown
Chemical Formula: C42H38F3N7O7S5
Exact Mass: 969.1388
Molecular Weight: 970.10
Elemental Analysis: C, 52.00; H, 3.95; F, 5.88; N, 10.11; O, 11.54; S, 16.52
The following data is based on the product molecular weight 970.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
