Synonym
Antibiotic OA 6129B(1); Antibiotic OA 6129B(sub 1); OA 6129B(2); OA-6129B(1); OA-6129B(2); OA-6129B1
IUPAC/Chemical Name
3-((2-(3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanamido)ethyl)thio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
InChi Key
HNLNYXRYILRJHY-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H31N3O8S/c1-10(25)14-11-8-12(15(19(30)31)23(11)18(14)29)32-7-6-21-13(26)4-5-22-17(28)16(27)20(2,3)9-24/h10-11,14,16,24-25,27H,4-9H2,1-3H3,(H,21,26)(H,22,28)(H,30,31)
SMILES Code
CC(C1C2CC(SCCNC(CCNC(C(C(C)(CO)C)O)=O)=O)=C(C(O)=O)N2C1=O)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
473.54
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Kojima I, Fukagawa Y, Okabe M, Ishikura T, Shibamoto N. Mutagenesis of OA-6129 carbapenem-producing blocked mutants and the biosynthesis of carbapenems. J Antibiot (Tokyo). 1988 Jul;41(7):899-907. doi: 10.7164/antibiotics.41.899. PMID: 3417564.
2. Fukagawa Y, Okabe M, Azuma S, Kojima I, Ishikura T, Kubo K. Studies on the biosynthesis of carbapenem antibiotics. I. Biosynthetic significance of the OA-6129 group of carbapenem compounds as the direct precursors for PS-5, epithienamycins A and C and MM 17880. J Antibiot (Tokyo). 1984 Nov;37(11):1388-93. doi: 10.7164/antibiotics.37.1388. PMID: 6511666.
3. Yoshioka T, Kojima I, Isshiki K, Watanabe A, Shimauchi Y, Okabe M, Fukagawa Y, Ishikura T. Structures of OA-6129A, B1, B2 and C, new carbapenem antibiotics produced by Streptomyces sp. OA-6129. J Antibiot (Tokyo). 1983 Nov;36(11):1473-82. doi: 10.7164/antibiotics.36.1473. PMID: 6654757.
