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MedKoo Cat#: 111500 | Name: Ethylenebisdithiocarbamic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ethylenebisdithiocarbamic acid is used as a pesticide and fungicide.

Chemical Structure

Ethylenebisdithiocarbamic acid
Ethylenebisdithiocarbamic acid
CAS#111-54-6

Theoretical Analysis

MedKoo Cat#: 111500

Name: Ethylenebisdithiocarbamic acid

CAS#: 111-54-6

Chemical Formula: C4H8N2S4

Exact Mass: 211.9600

Molecular Weight: 212.36

Elemental Analysis: C, 22.62; H, 3.80; N, 13.19; S, 60.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HSDB 6060; HSDB6060; HSDB-6060; Ethylenebis-dithiocarbamic acid; ethylenebisdithio carbamic acid; ethylenebisdithio-carbamic acid;
IUPAC/Chemical Name
ethane-1,2-diyldicarbamodithioic acid
InChi Key
AWYFNIZYMPNGAI-UHFFFAOYSA-N
InChi Code
InChI=1S/C4H8N2S4/c7-3(8)5-1-2-6-4(9)10/h1-2H2,(H2,5,7,8)(H2,6,9,10)
SMILES Code
SC(NCCNC(S)=S)=S
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 212.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li Y, Qi H, Li X, Hou X, Lu X, Xiao X. A novel dithiocarbamate derivative induces cell apoptosis through p53-dependent intrinsic pathway and suppresses the expression of the E6 oncogene of human papillomavirus 18 in HeLa cells. Apoptosis. 2015 Jun;20(6):787-95. doi: 10.1007/s10495-015-1114-4. PMID: 25772545. 2: Manfo FP, Nantia EA, Dechaud H, Tchana AN, Zabot MT, Pugeat M, Moundipa PF. Protective effect of Basella alba and Carpolobia alba extracts against maneb- induced male infertility. Pharm Biol. 2014 Jan;52(1):97-104. doi: 10.3109/13880209.2013.816860. Epub 2013 Sep 30. PMID: 24073857. 3: Innocenti A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1855-7. doi: 10.1016/j.bmcl.2009.02.088. Epub 2009 Feb 26. PMID: 19269822. 4: Hayama T, Takada M. Simple and rapid method for the determination of ethylenebisdithiocarbamate fungicides in fruits and vegetables using liquid chromatography with tandem mass spectrometry. Anal Bioanal Chem. 2008 Nov;392(5):969-76. doi: 10.1007/s00216-008-2346-8. Epub 2008 Aug 31. PMID: 18759101. 5: Zhou Y, Wang Y, Kovacs M, Jin J, Zhang J. Microglial activation induced by neurodegeneration: a proteomic analysis. Mol Cell Proteomics. 2005 Oct;4(10):1471-9. doi: 10.1074/mcp.M500114-MCP200. Epub 2005 Jun 22. PMID: 15975914. 6: Zhou Y, Shie FS, Piccardo P, Montine TJ, Zhang J. Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease. Neuroscience. 2004;128(2):281-91. doi: 10.1016/j.neuroscience.2004.06.048. PMID: 15350641. 7: Vryzas Z, Papadakis EN, Papadopoulou-Mourkidou E. Microwave-assisted extraction (MAE)-acid hydrolysis of dithiocarbamates for trace analysis in tobacco and peaches. J Agric Food Chem. 2002 Apr 10;50(8):2220-6. doi: 10.1021/jf0111864. PMID: 11929274. 8: Humeres E, Debacher NA, Sierra MM. Mechanisms of Acid Decomposition of Dithiocarbamates. 2. Efficiency of the Intramolecular General Acid Catalysis. J Org Chem. 1999 Mar 19;64(6):1807-1813. doi: 10.1021/jo981382i. PMID: 11674268. 9: van Lishaut H, Schwack W. Selective trace determination of dithiocarbamate fungicides in fruits and vegetables by reversed-phase ion-pair liquid chromatography with ultraviolet and electrochemical detection. J AOAC Int. 2000 May-Jun;83(3):720-7. PMID: 10868596. 10: Pastorelli R, Allevi R, Romagnano S, Meli G, Fanelli R, Airoldi L. Gas chromatography-mass spectrometry determination of ethylenethiourea hemoglobin adducts: a possible indicator of exposure to ethylene bis dithiocarbamate pesticides. Arch Toxicol. 1995;69(5):306-11. doi: 10.1007/s002040050175. PMID: 7654134. 11: Aggarwal SK, Kinter M, Herold DA. Determination of copper in urine and serum by gas chromatography-mass spectrometry. Anal Biochem. 1991 Apr;194(1):140-5. doi: 10.1016/0003-2697(91)90161-l. PMID: 1867378. 12: Miles CJ, Zhou M. Determination of nabam fungicide in crops by liquid chromatography with postcolumn reaction detection. J Assoc Off Anal Chem. 1991 Mar-Apr;74(2):384-8. PMID: 1904852. 13: Hajslová J, Kocourek V, Jehlicková Z, Davídek J. The fate of ethylenebis(dithiocarbamate) fungicides during processing of contaminated apples. Z Lebensm Unters Forsch. 1986 Nov;183(5):348-51. doi: 10.1007/BF01142545. PMID: 3811595. 14: Aerts J. Toxicological significance of impurities in pesticides. Arch Belg. 1985;43(3-4):144-55. PMID: 2415077. 15: Zaki MM, Mahmoud SA, Hamed AS, Sahab AF. Changes in metabolic activities of Fusarium oxysporum f. fabae and Rhizoctonia solani in response to Dithan A-40 fungicide. Zentralbl Bakteriol Naturwiss. 1979;134(8):660-5. doi: 10.1016/s0323-6056(79)80024-5. PMID: 543918. 16: Periquet A, de Saint-Blanquat G, Derache R, Souqual MC. Inflammation expérimentale après un traitement subchronique au Nabame chez le rat [Experimental inflammation after subchronic treatment with Nabam in the rat]. Toxicology. 1978 May;10(1):3-12. French. doi: 10.1016/0300-483x(78)90049-5. PMID: 150068. 17: Prahlad KV, Bancroft R, Hanzely L. Ultrastructural changes induced by the fungicide ethylenebis (dithiocarbamic acid)disodium salt (nabm(rabam) in Xenopus laevis tissues during development. Cytobios. 1974 Mar-Apr;9(35):121-30. PMID: 4858828. 18: Bancroft R, Prahlad KV. Effect of ethylenebis (dithiocarbamic acid)disodium salt(nabam)and ethylenebis(dithiocarbamato)manganese(maneb) on Xenopus laevis development. Teratology. 1973 Apr;7(2):143-50. doi: 10.1002/tera.1420070205. PMID: 4199117. 19: Fishbein L, Fawkes J. Thin-layer chromatography of metallic derivatives of ethylenebis(dithiocarbamic acid) and their degradation products. J Chromatogr. 1965 Aug;19(2):364-9. doi: 10.1016/s0021-9673(01)99471-3. PMID: 5859636. 20: CZERWINSKA E, KOWALIK R. Działanie etylenobisdwutiokarbaminianudwusdodowego (nabamu) i etylenobisdwutiokarbaminianu cynkowego (zinebu) na kilka grzybów niedoskonałych oraz na bakterie wia1zace azot atmosferyczny [Effect of ethylenebis[dithiocarbamic acid]sodium salt (nabam) and of ethylenebis[diethiocarbamic acid]zinc salt (zineb) on fungi imperfecti and on bacteria binding nitrogen in air]. Acta Microbiol Pol (1952). 1955;4(2):141-51. Polish. PMID: 14387599.