Brombuterol HCl | CAS#21912-49-2 | β2-AR agonist

MedKoo Cat#: 464712 | Name: Brombuterol HCl

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Brombuterol is an agonist of the β2-adrenergic receptor (β2-AR). It has been used as an illicit feed additive to increase the muscle-to-fat ratio of livestock.

Chemical Structure

Brombuterol HCl

CAS#21912-49-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 464712

Name: Brombuterol HCl

CAS#: 21912-49-2 (HCl)

Chemical Formula: C12H19Br2ClN2O

Exact Mass: 399.9553

Molecular Weight: 402.56

Elemental Analysis: C, 35.80; H, 4.76; Br, 39.70; Cl, 8.81; N, 6.96; O, 3.97

Price and Availability

Size	Price	Availability
5mg	USD 385.00	2 Weeks
10mg	USD 700.00	2 Weeks
25mg	USD 1,250.00	2 Weeks

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Related CAS #

No Data

Synonym

Brombuterol HCl; Brombuterol hydrochloride;

IUPAC/Chemical Name

1-(4-amino-3,5-dibromophenyl)-2-(tert-butylamino)ethan-1-ol hydrochloride

InChi Key

XGPFKIAOVSGRSY-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H18Br2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

SMILES Code

BrC1=C(C(Br)=CC(C(O)CNC(C)(C)C)=C1)N.Cl

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 402.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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Mikrochim Acta. 2018;185(3):191. doi: 10.1007/s00604-018-2730-9. Epub 2018 Feb 22. PMID: 29503465; PMCID: PMC5823949. 11: Chu L, Zheng S, Qu B, Geng S, Kang X. Detection of β-agonists in pork tissue with novel electrospun nanofibers-based solid-phase extraction followed ultra- high performance liquid chromatography/tandem mass spectrometry. Food Chem. 2017 Jul 15;227:315-321. doi: 10.1016/j.foodchem.2017.01.059. Epub 2017 Jan 16. PMID: 28274437. 12: Ren Z, Chen Y, Wang J, Zheng P, Zhang H, Jiang H. A highly specific and sensitive indirect competitive monoclonal ELISA for the detection of brombuterol in animal feed, swine urine, pork and liver samples. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Apr;38(4):586-593. doi: 10.1080/19440049.2021.1877835. Epub 2021 Feb 17. PMID: 33596157. 13: Suo DC, Zhao GL, Wang PL, Su XO. Simultaneous determination of β-agonists and psychiatric drugs in feeds by LC-MS-MS. 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