Synonym
Nifursemizone; NF161; NF 161; NF-161
IUPAC/Chemical Name
1-Ethyl-2-((5-nitro-2-furanyl)methylene)hydrazinecarboxamide
InChi Key
JGPNCLKRECLYTO-BJMVGYQFSA-N
InChi Code
InChI=1S/C8H10N4O4/c1-2-11(8(9)13)10-5-6-3-4-7(16-6)12(14)15/h3-5H,2H2,1H3,(H2,9,13)/b10-5+
SMILES Code
O=[N+](C1=CC=C(/C=N/N(C(N)=O)CC)O1)[O-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
226.19
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Dianzani C, Collino M, Gallicchio M, Di Braccio M, Roma G, Fantozzi R. Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study. J Inflamm (Lond). 2006 Mar 28;3:4. doi: 10.1186/1476-9255-3-4. PMID: 16569220; PMCID: PMC1435878.
2: Sokawa Y, Sokawa J, Kaziro Y. Regulation of stable RNA synthesis and ppGpp levels in growing cells of Escherichia coli. Cell. 1975 May;5(1):69-74. doi: 10.1016/0092-8674(75)90093-8. PMID: 1093696.
3: Kodaki T, Murakami H, Taguchi M, Izui K, Katsuki H. Stringent control of intermediary metabolism in Escherichia coli: pyruvate excretion by cells grown on succinate. J Biochem. 1981 Nov;90(5):1437-44. doi: 10.1093/oxfordjournals.jbchem.a133610. PMID: 7040357.
4: Mach H, Hecker M, Hill I, Schroeter A, Mach F. Physiologische Bedeutung der "Stringent Control" bei Escherichia coli unter extremen Hungerbedingungen [Physiologic significance of "stringent control" in Escherichia coli under extreme starvation]. Z Naturforsch C J Biosci. 1989 Sep-Oct;44(9-10):838-44. German. PMID: 2686672.
5: Sy J. In vitro degradation of guanosine 5'-diphosphate, 3'-diphosphate. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5529-33. doi: 10.1073/pnas.74.12.5529. PMID: 414222; PMCID: PMC431794.
6: Jacobson LA, Jen-Jacobson L. Control of protein synthesis in Escherichia coli: strain differences in control of translational initiation after energy source shift-down. J Bacteriol. 1980 Jun;142(3):888-98. doi: 10.1128/JB.142.3.888-898.1980. PMID: 6155375; PMCID: PMC294114.
