MedKoo Cat#: 559351 | Name: Macluraxanthone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Macluraxanthone, a xanthone derivative, was previously reported to have many biological activities, including anti-cholinesterase, anti-oxidant, anti-cancer, anti-malarial and anti-inflammatory effects.

Chemical Structure

Macluraxanthone
Macluraxanthone
CAS#5848-14-6

Theoretical Analysis

MedKoo Cat#: 559351

Name: Macluraxanthone

CAS#: 5848-14-6

Chemical Formula: C23H22O6

Exact Mass: 394.1416

Molecular Weight: 394.42

Elemental Analysis: C, 70.04; H, 5.62; O, 24.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Macluraxanthone; NSC 107228; NSC107228; NSC-107228
IUPAC/Chemical Name
2H,6H-Pyrano(3,2-b)xanthen-6-one, 12-(1,1-dimethyl-2-propenyl)-5,9,10-trihydroxy-2,2-dimethyl-
InChi Key
XRVLGJCHUWXTDX-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H22O6/c1-6-22(2,3)15-19-12(9-10-23(4,5)29-19)17(26)14-16(25)11-7-8-13(24)18(27)20(11)28-21(14)15/h6-10,24,26-27H,1H2,2-5H3
SMILES Code
CC(C)(C=C)c1c2Oc3c(O)c(O)ccc3C(=O)c2c(O)c4C=CC(C)(C)Oc14
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 394.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Ng IMJ, Mah SH, Chua CLL. Immuno-modulatory effects of macluraxanthone on macrophage phenotype and function. Nat Prod Res. 2020 Jun 8:1-6. doi: 10.1080/14786419.2020.1775223. Epub ahead of print. PMID: 32508145. 2. Xiang Q, Wu M, Zhang L, Fu W, Yang J, Zhang B, Zheng Z, Zhang H, Lao Y, Xu H. Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury. Front Pharmacol. 2020 Apr 15;11:452. doi: 10.3389/fphar.2020.00452. PMID: 32351391; PMCID: PMC7175665.