MedKoo Cat#: 414069 | Name: Nicofuranose
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nicofuranose is a derivative of nicotinic acid that produces fewer side effects than pure nicotinic acid; used in peripheral vascular disease; also proposed as anticholesteremic.

Chemical Structure

Nicofuranose
CAS#15351-13-0

Theoretical Analysis

MedKoo Cat#: 414069

Name: Nicofuranose

CAS#: 15351-13-0

Chemical Formula: C30H24N4O10

Exact Mass: 600.1492

Molecular Weight: 600.54

Elemental Analysis: C, 60.00; H, 4.03; N, 9.33; O, 26.64

Price and Availability

Size Price Availability Quantity
25g USD 235.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Nicofuranose; ES304; ES-304; ES 304
IUPAC/Chemical Name
(2R,3S,4R,5R)-2-hydroxy-2,5-bis((nicotinoyloxy)methyl)tetrahydrofuran-3,4-diyl dinicotinate
InChi Key
FUWFSXZKBMCSKF-ZASNTINBSA-N
InChi Code
InChI=1S/C30H24N4O10/c35-26(19-5-1-9-31-13-19)40-17-23-24(42-28(37)21-7-3-11-33-15-21)25(43-29(38)22-8-4-12-34-16-22)30(39,44-23)18-41-27(36)20-6-2-10-32-14-20/h1-16,23-25,39H,17-18H2/t23-,24-,25+,30-/m1/s1
SMILES Code
O[C@@]1(O[C@@H]([C@H]([C@@H]1OC(c2cnccc2)=O)OC(c3cnccc3)=O)COC(c4cnccc4)=O)COC(c5cnccc5)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Nicofuranose is a derivative of nicotinic acid that produces fewer side effects than pure nicotinic acid.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 600.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Salmi HA, Frey H. Nicotinic acid plasma concentrations after ingestion of 1,3,4,6-tetranicotinoyl-fructo-furanose (tetranicotinoylfructose, nicofuranose). Curr Ther Res Clin Exp. 1974 Jun;16(6):669-74. PMID: 4211148. 2: Pankiewicz F. Beitrag zur Therapie von Durchblutungsstörungen mit Tetranicotinoyl-fructofuranose (Nicofuranose) [Contribution to the therapy of blood circulation disorders with tetranicotinoyl-fructofuranose (Nicofuranose)]. Ther Umsch. 1965 Oct;22(10):494-7. German. PMID: 5882062. 3: RABASSINI A, BUOSO M. SULL'IMPIEGO DI UN'ASSOCIAZIONE DI CENTROFENOXINA E DI TETRANICOTINOILFRUTTOSISO IN PSICHIATRIA [ON THE USE OF AN ASSOCIATION OF CENTROPHENOXINE AND TETRANICOTINOYLFRUCTOSE IN PSYCHIATRY]. Minerva Med. 1965 Jul 21;56:2467-72. Italian. PMID: 14344282. 4: ORICOLI L. PROBLEMI TERAPEUTICI IN TEMA DI ARTERIOPATIE OBLITERANTI DEGLI ARTI INFERIORI: ESPERIENZE PERSONALI CON UN DERIVATO DELL'ACIDO NICOTINICO, IL TETRANICOTINOIL-FRUTTOSIO (BRADILAN) [THERAPEUTIC PROBLEMS ON THE SUBJECT OF OBLITERATING ARTERIAL DISEASES OF THE LEGS: PERSONAL EXPERIENCES WITH A NICOTINIC ACID DERIVATIVE, TETRANICOTINOYL FRUCTOSE (BRADILAN)]. Osp Ital Chir. 1965 Jan;12:71-82. Italian. PMID: 14299158. 5: VALLSSERRA J. ESTUDIO CL'INICO DE LA TETRANICOTINOYL-FRUCTOSA EN EL TRATAMIENTO DE LAS ANGIOPATIAS PERIF'ERICAS [CLINICAL STUDY OF TETRANICOTINOYLFRUCTOSE IN THE TREATMENT OF PERIPHERAL ANGIOPATHIES]. Med Clin (Barc). 1964 Feb;42:100-9. Spanish. PMID: 14163682. 6: PORTELLA A, SCARDINO R. [Study of a new nicotinic acid derivative (Bradilan) with special reference to its tolerability]. Rass Int Clin Ter. 1963 Apr 30;43:433-40. Italian. PMID: 13972344. 7: Fedorocko P, Macková NO, Sándorcínová Z, Sedláková-Hoferová Z, Solár P, Chlebovský O. Influence of age and K, Mg aspartate (Cardilan) on murine haemopoiesis. Mech Ageing Dev. 2000 Nov 15;119(3):159-70. doi: 10.1016/s0047-6374(00)00175-5. PMID: 11080535. 8: KOWALSKA M. VASPERDIL IN DER BEHANDLUNG PERIPHERER GEFAESSERKRANKUNGEN [VASPERDIL IN THE TREATMENT OF PERIPHERAL VASCULAR DISEASES]. Ther Umsch. 1964 Aug;21:310-1. German. PMID: 14299958.