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MedKoo Cat#: 559321 | Name: Musettamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Musettamycin is a potent inducer of erythroid differentiation in hemopoietic cells lines of rodent and human origin. It also has antimicrobial effects similar to the anthracycline class since it inhibits gram-positive bacteria and typically doesn't affect gram-negative bacteria.

Chemical Structure

Musettamycin
Musettamycin
CAS#63710-09-8

Theoretical Analysis

MedKoo Cat#: 559321

Name: Musettamycin

CAS#: 63710-09-8

Chemical Formula: C36H45NO14

Exact Mass: 715.2840

Molecular Weight: 715.75

Elemental Analysis: C, 60.41; H, 6.34; N, 1.96; O, 31.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Musettamycin; 1-Hydroxy MA144 S1; Antibiotic MA 144S2; CCRIS 2265; MA144 S2; 1-Hydroxy MA 144 S1; Antibiotic MA 144 S2; CCRIS-2265; MA 144 S2; 1-Hydroxy MA-144 S1; Antibiotic MA-144S2; CCRIS2265; MA-144 S2
IUPAC/Chemical Name
1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((4-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester
InChi Key
PXKJRTZJMGPOGS-YBVXKORNSA-N
InChi Code
InChI=1S/C36H45NO14/c1-7-36(46)13-22(50-23-11-18(37(4)5)34(15(3)49-23)51-24-12-21(40)30(41)14(2)48-24)25-16(29(36)35(45)47-6)10-17-26(32(25)43)33(44)28-20(39)9-8-19(38)27(28)31(17)42/h8-10,14-15,18,21-24,29-30,34,38-41,43,46H,7,11-13H2,1-6H3/t14-,15?,18-,21-,22-,23-,24-,29-,30+,34+,36+/m0/s1
SMILES Code
CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O[C@H]3C[C@H](O)[C@H](O)[C@H](C)O3)C(C)O2)N(C)C)c4c(O)c5C(=O)c6c(O)ccc(O)c6C(=O)c5cc4[C@H]1C(=O)OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 715.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Steinheider G, Westendorf J, Marquardt H. Induction of erythroid differentiation by the anthracycline antitumor antibiotics, aclacinomycin A, musettamycin and marcellomycin. Leuk Res. 1986;10(10):1233-9. doi: 10.1016/0145-2126(86)90242-0. PMID: 3464812. Nettleton DE Jr, Balitz DM, Doyle TW, Bradner WT, Johnson DL, O'Herron FA, Schreiber RH, Coon AB, Moseley JE, Myllymaki RW. Antitumor agents from bohemic acid complex, III. The isolation of marcellomycin, musettamycin, rudolphomycin, mimimycin, collinemycin, alcindoromycin, and bohemamine. J Nat Prod. 1980 Mar-Apr;43(2):242-58. doi: 10.1021/np50008a003. PMID: 7381507.