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MedKoo Cat#: 414066 | Name: Ermanin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ermanin has a role as an anti-inflammatory agent, an antimycobacterial drug, an apoptosis inducer, an antineoplastic agent and a plant metabolite.

Chemical Structure

Ermanin
Ermanin
CAS#20869-95-8

Theoretical Analysis

MedKoo Cat#: 414066

Name: Ermanin

CAS#: 20869-95-8

Chemical Formula: C17H14O6

Exact Mass: 314.0790

Molecular Weight: 314.29

Elemental Analysis: C, 64.97; H, 4.49; O, 30.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ermanin; NSC31882; NSC-31882; NSC 31882
IUPAC/Chemical Name
5,7-Dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4-benzopyrone
InChi Key
RJCJVIFSIXKSAH-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H14O6/c1-21-11-5-3-9(4-6-11)16-17(22-2)15(20)14-12(19)7-10(18)8-13(14)23-16/h3-8,18-19H,1-2H3
SMILES Code
O=C1C(OC)=C(C2=CC=C(OC)C=C2)OC3=CC(O)=CC(O)=C13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 314.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Appunni S, Rajisha PM, Rubens M, Chandana S, Singh HN, Swarup V. Targeting PknB, an eukaryotic-like serine/threonine protein kinase of Mycobacterium tuberculosis with phytomolecules. Comput Biol Chem. 2017 Apr;67:200-204. doi: 10.1016/j.compbiolchem.2017.01.003. Epub 2017 Jan 9. PMID: 28131886. 2: Mata R, Bye R, Linares E, Macías M, Rivero-Cruz I, Pérez O, Timmermann BN. Phytotoxic compounds from Flourensia cernua. Phytochemistry. 2003 Sep;64(1):285-91. doi: 10.1016/s0031-9422(03)00217-6. PMID: 12946427. 3: Chen JJ, Tsai TH, Liao HR, Chen LC, Kuo YH, Sung PJ, Chen CL, Wei CS. New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria. Molecules. 2016 Oct 17;21(10):1385. doi: 10.3390/molecules21101385. PMID: 27763530; PMCID: PMC6272984. 4: Abad MJ, Bermejo P, Alvarez M, Guerra JA, Silván AM, Villar AM. Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti- inflammatory mediators in LPS-stimulated mouse peritoneal macrophages. Planta Med. 2004 Jan;70(1):34-8. doi: 10.1055/s-2004-815452. PMID: 14765290. 5: Guerra JA, Molina M, Abad MJ, Villar AM, Paulina B. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum. Int Immunopharmacol. 2006 Nov;6(11):1723-8. doi: 10.1016/j.intimp.2006.07.012. Epub 2006 Aug 10. PMID: 16979127. 6: da Silva Filho AA, Resende DO, Fukui MJ, Santos FF, Pauletti PM, Cunha WR, Silva ML, Gregório LE, Bastos JK, Nanayakkara NP. In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae). Fitoterapia. 2009 Dec;80(8):478-82. doi: 10.1016/j.fitote.2009.06.007. Epub 2009 Jun 18. PMID: 19540316. 7: Saepou S, Pohmakotr M, Reutrakul V, Yoosook C, Kasisit J, Napaswad C, Tuchinda P. Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla. Planta Med. 2010 May;76(7):721-5. doi: 10.1055/s-0029-1240683. Epub 2009 Dec 14. PMID: 20013639. 8: Okińczyc P, Widelski J, Szperlik J, Żuk M, Mroczek T, Skalicka-Woźniak K, Sakipova Z, Widelska G, Kuś PM. Impact of Plant Origin on Eurasian Propolis on Phenolic Profile and Classical Antioxidant Activity. Biomolecules. 2021 Jan 6;11(1):68. doi: 10.3390/biom11010068. PMID: 33419208; PMCID: PMC7825625. 9: Kyriakopoulou I, Magiatis P, Skaltsounis AL, Aligiannis N, Harvala C. Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia. J Nat Prod. 2001 Aug;64(8):1095-7. doi: 10.1021/np010128+. PMID: 11520237. 10: Silván AM, Abad MJ, Bermejo P, Villar A. Effects of compounds extracted from Tanacetum microphyllum on arachidonic acid metabolism in cellular systems. Planta Med. 1998 Apr;64(3):200-3. doi: 10.1055/s-2006-957408. PMID: 9581513.