FS2921 | CAS#unknown | NMDAR PAM

MedKoo Cat#: 464687 | Name: FS2921

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FS2921 is a novel NMDAR PAM with potential antidepressant effects.

Chemical Structure

FS2921

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464687

Name: FS2921

CAS#: unknown

Chemical Formula: C18H18BrN3O2

Exact Mass: 387.0582

Molecular Weight: 388.27

Elemental Analysis: C, 55.68; H, 4.67; Br, 20.58; N, 10.82; O, 8.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FS2921; FS 2921; FS-2921;

IUPAC/Chemical Name

N-(4-bromo-2-methylphenyl)-5-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)furan-2-carboxamide

InChi Key

ZHLZILZVGZCQNG-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H18BrN3O2/c1-11-8-14(19)4-6-16(11)20-18(23)17-7-5-15(24-17)10-22-13(3)9-12(2)21-22/h4-9H,10H2,1-3H3,(H,20,23)

SMILES Code

O=C(NC1=CC=C(Br)C=C1C)C2=CC=C(CN3C(C)=CC(C)=N3)O2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 388.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Li Z, Cai G, Fang F, Li W, Fan M, Lian J, Qiu Y, Xu X, Lv X, Li Y, Zheng R, Wang Y, Li Z, Zhang G, Liu Z, Huang Z, Zhang L. Discovery of Novel and Potent N-Methyl-d-aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent Models. J Med Chem. 2021 May 3. doi: 10.1021/acs.jmedchem.0c02018. Epub ahead of print. PMID: 33934604.