MedKoo Cat#: 464656 | Name: RJN00281

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RJN00281 is a novel anti-Parkinson agent, targeting the D2R. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

RJN00281
RJN00281
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464656

Name: RJN00281

CAS#: unknown

Chemical Formula: C13H19N3O4

Exact Mass: 281.1376

Molecular Weight: 281.31

Elemental Analysis: C, 55.51; H, 6.81; N, 14.94; O, 22.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
RJN00281; RJN 00281; RJN-00281; 3-Furoyl-L-leucylglycinamide;
IUPAC/Chemical Name
(S)-N-(1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)furan-3-carboxamide
InChi Key
RYAUDQTUUTVOSS-JTQLQIEISA-N
InChi Code
InChI=1S/C13H19N3O4/c1-8(2)5-10(13(19)15-6-11(14)17)16-12(18)9-3-4-20-7-9/h3-4,7-8,10H,5-6H2,1-2H3,(H2,14,17)(H,15,19)(H,16,18)/t10-/m0/s1
SMILES Code
O=C(NCC(N)=O)[C@H](CC(C)C)NC(C1=COC=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 281.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sampaio-Dias IE, Reis-Mendes A, Costa VM, García-Mera X, Brea J, Loza MI, Pires-Lima BL, Alcoholado C, Algarra M, Rodríguez-Borges JE. Discovery of New Potent Positive Allosteric Modulators of Dopamine D2 Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide. J Med Chem. 2021 Apr 16. doi: 10.1021/acs.jmedchem.1c00252. Epub ahead of print. PMID: 33861612.