Patamostat is a protease inhibitor in vivo and in vitro. Inhibitory activity was shown toward trypsin, thrombin, plasmin, cathepsin-B and kallikrein. Patamostat is effective toward experimental pancreatitis and disseminated intravascular coagulation (animal models).
MedKoo Cat#: 413982
Name: Patamostat
CAS#: 114568-26-2 (free base)
Chemical Formula: C20H20N4O4S
Exact Mass: 412.1205
Molecular Weight: 412.46
Elemental Analysis: C, 58.24; H, 4.89; N, 13.58; O, 15.52; S, 7.77
The following data is based on the product molecular weight 412.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
