RL-338 is a novel potent and highly selective GPR6 inverse agonist, inhibiting GPR6 cAMP signalling in TR-FRET assays with a EC50 = 16 nM and >100 fold selectivity against GPR3 and GPR12.
MedKoo Cat#: 464647
Name: RL-338
CAS#: unknown
Chemical Formula: C21H25FN6O2
Exact Mass: 412.2023
Molecular Weight: 412.47
Elemental Analysis: C, 61.15; H, 6.11; F, 4.61; N, 20.38; O, 7.76
The following data is based on the product molecular weight 412.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
