HY1-Pt | CAS#unknown | DNA Damage Repair suppressor

MedKoo Cat#: 464629 | Name: HY1-Pt

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HY1-Pt is a novel CK2-Specific Pt(II) Compound, Reversing Cisplatin-Induced Resistance by Inhibiting Cancer Cell Stemness and Suppressing DNA Damage Repair in Non-small Cell Lung Cancer Treatments

Chemical Structure

HY1-Pt

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464629

Name: HY1-Pt

CAS#: unknown

Chemical Formula: C25H22ClN7O5Pt

Exact Mass: 730.1019

Molecular Weight: 731.03

Elemental Analysis: C, 41.08; H, 3.03; Cl, 4.85; N, 13.41; O, 10.94; Pt, 26.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HY1-Pt; HY1Pt; HY1 Pt;

IUPAC/Chemical Name

N/A

InChi Key

UABNNLOZDHSKMR-UHFFFAOYSA-L

InChi Code

InChI=1S/C25H18ClN5O5.2H3N.Pt/c26-14-2-1-3-15(9-14)28-21-18-6-7-27-12-19(18)17-5-4-13(8-20(17)29-21)22(32)31-30-16-10-25(11-16,23(33)34)24(35)36;;;/h1-9,12H,10-11H2,(H,28,29)(H,31,32)(H,33,34)(H,35,36);2*1H3;/q;;;+2/p-2

SMILES Code

ClC1=CC=CC(NC2=NC3=C(C=CC(C(N/N=C4CC5(C(O[Pt]([NH3])([NH3])OC5=O)=O)C\4)=O)=C3)C6=C2C=CN=C6)=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 731.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang Y, Wang X, Xu G, Gou S. Novel CK2-Specific Pt(II) Compound Reverses Cisplatin-Induced Resistance by Inhibiting Cancer Cell Stemness and Suppressing DNA Damage Repair in Non-small Cell Lung Cancer Treatments. J Med Chem. 2021 Apr 8;64(7):4163-4178. doi: 10.1021/acs.jmedchem.1c00079. Epub 2021 Mar 30. PMID: 33784109.