XRN34435 is an inhibitor of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism (IC50 = 12 nM). XRN34435 was first reported in Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):719-24 (compound 15). This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 556001
Name: XRN34435
CAS#: 916734-43-5
Chemical Formula: C23H28N4O6S2
Exact Mass: 520.1450
Molecular Weight: 520.62
Elemental Analysis: C, 53.06; H, 5.42; N, 10.76; O, 18.44; S, 12.32
The following data is based on the product molecular weight 520.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
