MedKoo Cat#: 555977 | Name: ZUN64390
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZUN64390, also known as PI3Kδ-IN-1, is a potent, selective, and efficacious PI3Kδ inhibitor with an IC50 of 1.7 nM. ZUN64390 was first reported in J Med Chem. 2017 Jun 22;60(12):5193-5208. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

ZUN64390
ZUN64390
CAS#1911564-39-0

Theoretical Analysis

MedKoo Cat#: 555977

Name: ZUN64390

CAS#: 1911564-39-0

Chemical Formula: C22H20F3N7O2

Exact Mass: 471.1631

Molecular Weight: 471.44

Elemental Analysis: C, 56.05; H, 4.28; F, 12.09; N, 20.80; O, 6.79

Price and Availability

Size Price Availability Quantity
500mg USD 2,950.00 2 Weeks
1g USD 3,950.00 2 Weeks
2g USD 5,950.00 2 Weeks
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Synonym
PI3Kδ-IN-1; PI3Kδ-IN 1; ZUN64390; ZUN-64390; ZUN 64390;
IUPAC/Chemical Name
2-(4-acetyl-3,3-dimethyl-2-oxopiperazin-1-yl)-4-(4-amino-5-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)benzonitrile
InChi Key
ZDXIDBRGTYDHBQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H20F3N7O2/c1-12(33)31-7-6-30(20(34)21(31,2)3)16-8-13(4-5-14(16)10-26)17-9-15(22(23,24)25)18-19(27)28-11-29-32(17)18/h4-5,8-9,11H,6-7H2,1-3H3,(H2,27,28,29)
SMILES Code
NC1=NC=NN2C1=C(C(F)(F)F)C=C2C3=CC=C(C#N)C(N4CCN(C(C)=O)C(C)(C)C4=O)=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 471.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
[1]. Liu Q, et al. Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders. J Med Chem. 2017 Jun 22;60(12):5193-5208.