MedKoo Cat#: 413876 | Name: Dobupride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dobupride is a novel gastroprokinetic drug. Dobupride has shown powerful gastroprokinetic activity in animal studies, inducing gastric emptying and intestinal motility and increasing the resting pressure of the lower oesophageal sphincter.

Chemical Structure

Dobupride
Dobupride
CAS#106707-51-1

Theoretical Analysis

MedKoo Cat#: 413876

Name: Dobupride

CAS#: 106707-51-1

Chemical Formula: C20H30ClN3O4

Exact Mass: 411.1925

Molecular Weight: 411.93

Elemental Analysis: C, 58.32; H, 7.34; Cl, 8.61; N, 10.20; O, 15.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Dobupride; Dobupridum; Dobuprida
IUPAC/Chemical Name
4-Amino-2-butoxy-5-chloro-N-(1-(1,3-dioxolan-2-ylmethyl)-4-piperidyl)benzamide
InChi Key
BTBFXLRQGPHRGT-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H30ClN3O4/c1-2-3-8-26-18-12-17(22)16(21)11-15(18)20(25)23-14-4-6-24(7-5-14)13-19-27-9-10-28-19/h11-12,14,19H,2-10,13,22H2,1H3,(H,23,25)
SMILES Code
O=C(NC1CCN(CC2OCCO2)CC1)C3=CC(Cl)=C(N)C=C3OCCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 411.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Singh S. Dobupride--what exactly is its degradation behavior? J Pharm Biomed Anal. 1997 Jul;15(11):1801-3. doi: 10.1016/s0731-7085(96)01949-8. PMID: 9260678. 2: Segarra V, Carrera F, Fabregas JL, Claramunt J. Degradation profile and identification of the major degradation products of dobupride under several conditions by GC/MS and HPLC-particle beam/MS. J Pharm Biomed Anal. 1995 Jul;13(8):987-93. doi: 10.1016/0731-7085(95)01521-l. PMID: 8580158. 3: McFalls EO, Murad B, Her D, Liow JS, Kelly R, Marx D, Sikora J, Ward HB. Repetitive supply-demand ischemia with dobutamine increases glucose uptake in postischemic and remote myocardium. J Nucl Med. 2003 Jan;44(1):85-91. PMID: 12515880.