MedKoo Cat#: 413873 | Name: FG 9041
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FG 9041 is a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively).

Chemical Structure

FG 9041
FG 9041
CAS#2379-57-9

Theoretical Analysis

MedKoo Cat#: 413873

Name: FG 9041

CAS#: 2379-57-9

Chemical Formula: C8H4N4O6

Exact Mass: 252.0131

Molecular Weight: 252.14

Elemental Analysis: C, 38.11; H, 1.60; N, 22.22; O, 38.07

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
100mg USD 550.00 2 Weeks
200mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
FG 9041; FG9041; FG-9041; DNQX;
IUPAC/Chemical Name
2,3-Quinoxalinedione, 1,4-dihydro-6,7-dinitro-
InChi Key
RWVIMCIPOAXUDG-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14)
SMILES Code
O=C1NC2=C(C=C([N+]([O-])=O)C([N+]([O-])=O)=C2)NC1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Birch PJ, Grossman CJ, Hayes AG. Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors. Eur J Pharmacol. 1988 Jul 7;151(2):313-5. doi: 10.1016/0014-2999(88)90814-x. PMID: 2901972. 2: Fletcher EJ, Martin D, Aram JA, Lodge D, Honoré T. Quinoxalinediones selectively block quisqualate and kainate receptors and synaptic events in rat neocortex and hippocampus and frog spinal cord in vitro. Br J Pharmacol. 1988 Oct;95(2):585-97. doi: 10.1111/j.1476-5381.1988.tb11680.x. PMID: 2906560; PMCID: PMC1854198. 3: Aram JA, Martin D, Tomczyk M, Zeman S, Millar J, Pohler G, Lodge D. Neocortical epileptogenesis in vitro: studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands. J Pharmacol Exp Ther. 1989 Jan;248(1):320-8. PMID: 2536430.