MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 413857 | Name: DK-507K

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DK-507K is a biochemical with antibacterial activities.

Chemical Structure

DK-507K
DK-507K
CAS#364069-14-7

Theoretical Analysis

MedKoo Cat#: 413857

Name: DK-507K

CAS#: 364069-14-7

Chemical Formula: C20H21F2N3O4

Exact Mass: 405.1500

Molecular Weight: 405.40

Elemental Analysis: C, 59.25; H, 5.22; F, 9.37; N, 10.37; O, 15.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
DK507K; DK 507K; DK-507K
IUPAC/Chemical Name
3-Quinolinecarboxylic acid, 7-((7S)-7-amino-5-azaspiro(2.4)hept-5-yl)-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-1,4-dihydro-8-methoxy-4-oxo-
InChi Key
JYRHGXXQSIPDDP-IACUBPJLSA-N
InChi Code
InChI=1S/C20H21F2N3O4/c1-29-18-15-9(17(26)10(19(27)28)6-25(15)13-5-11(13)21)4-12(22)16(18)24-7-14(23)20(8-24)2-3-20/h4,6,11,13-14H,2-3,5,7-8,23H2,1H3,(H,27,28)/t11-,13+,14+/m0/s1
SMILES Code
O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@H]4N)CC54CC5)=C3OC)C1=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 405.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Otani T, Tanaka M, Ito E, Kurosaka Y, Murakami Y, Onodera K, Akasaka T, Sato K. In vitro and in vivo antibacterial activities of DK-507k, a novel fluoroquinolone. Antimicrob Agents Chemother. 2003 Dec;47(12):3750-9. doi: 10.1128/aac.47.12.3750-3759.2003. PMID: 14638477; PMCID: PMC296186. 2: Browne FA, Bozdogan B, Clark C, Kelly LM, Ednie L, Kosowska K, Dewasse B, Jacobs MR, Appelbaum PC. Antipneumococcal activity of DK-507k, a new quinolone, compared with the activities of 10 other agents. Antimicrob Agents Chemother. 2003 Dec;47(12):3815-24. doi: 10.1128/aac.47.12.3815-3824.2003. PMID: 14638489; PMCID: PMC296219. 3: Bozdogan B, Esel D, Whitener C, Browne FA, Appelbaum PC. Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus strain isolated at the Hershey Medical Center. J Antimicrob Chemother. 2003 Nov;52(5):864-8. doi: 10.1093/jac/dkg457. Epub 2003 Oct 16. PMID: 14563898. 4: Itoh S, Nakayama S, Shimada H. In vitro photochemical clastogenicity of quinolone antibacterial agents studied by a chromosomal aberration test with light irradiation. Mutat Res. 2002 May 27;517(1-2):113-21. doi: 10.1016/s1383-5718(02)00058-x. PMID: 12034313.