MedKoo Cat#: 464566 | Name: GNF-Pf-3600

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GNF-Pf-3600 is a novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites.

Chemical Structure

GNF-Pf-3600
GNF-Pf-3600
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464566

Name: GNF-Pf-3600

CAS#: unknown

Chemical Formula: C20H17FN2O3

Exact Mass: 352.1223

Molecular Weight: 352.37

Elemental Analysis: C, 68.17; H, 4.86; F, 5.39; N, 7.95; O, 13.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GNF-Pf-3600; GNFPf-3600; GNF Pf-3600; GNF-Pf3600; GNF-Pf 3600; GNFPf3600; GNF Pf 3600;
IUPAC/Chemical Name
N-(3-(dimethylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(4-fluorophenyl)acetamide
InChi Key
FVRIOJHLLBBMAD-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H17FN2O3/c1-12(24)23(14-10-8-13(21)9-11-14)18-17(22(2)3)19(25)15-6-4-5-7-16(15)20(18)26/h4-11H,1-3H3
SMILES Code
CC(N(C(C1=O)=C(N(C)C)C(C2=C1C=CC=C2)=O)C3=CC=C(F)C=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 352.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rocamora F, Gupta P, Istvan ES, Luth MR, Carpenter EF, Kümpornsin K, Sasaki E, Calla J, Mittal N, Carolino K, Owen E, Llinás M, Ottilie S, Goldberg DE, Lee MCS, Winzeler EA. PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum. ACS Infect Dis. 2021 Apr 9;7(4):811-825. doi: 10.1021/acsinfecdis.0c00676. Epub 2021 Mar 14. PMID: 33715347; PMCID: PMC8042660.